Exhibit 2 Company Milestones-authorized for educator review

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Exhibit 2 Company Milestones
1996 Merger of Ciba-Geigy and Sandoz to create one of the largest healthcare companies
2002 Novartis Institutes for Biomedical Research (NIBR) is created, headquartered in the United States
2003 Acquisition of Mead Johnson & Co., a subsidiary of Bristol-Myers Squibb
2004 Novartis submits Xolair for EU approval for treatment of allergic asthma
NIBR announces joint project with the Broad Institute of MIT and Harvard to research type 2 diabetes
2005 Landmark trial on Gleevec/Glivec, to treat chronic myeloid leukemia, shows 90% of patients still alive after four years of treatment
Aclasta gains EU regulation approval for treatment of Paget’s bone disease
Acquired North American over the counter brand portfolio of Bristol-Myers Squibb, expanding Novartis’ presence
2006 Strategic biomedical R&D center opens in Shanghai
Novartis Institute for Tropical Disease (NITD) initiates research on malaria. Through partnership with World Health Organization (WHO), provides anti-malarial Coartem, for no charge in developing nations
Omnitrope receives European Commission approval; 1st product approved under the EU’s new regulatory pathway for follow-on biological products
2007 Completed non-core divestments of the Gerber and Medical Nutrition Business units to Nestlé for $5.5 billion and $2.5 billion, respectively
Ranked No. 1 among pharmaceutical companies in Fortune magazine’s “World’s Most Admired Companies” survey
2008 Novartis announced an agreement to acquire 25% interest in Alcon, Inc., world leader in eye care with pharmaceutical, surgical, and consumer products (majority ownership acquired in 2010 and 100% in 2011)
Opened new vaccine research institute in Siena, Italy
Named healthcare super sector leader in the 2008 update of the Dow Jones Sustainability World Index
2009 Novartis became the first company to produce influence A (H1N1) vaccines with modern cell-culture biotechnology
Announced $1 billion investment over five years in China to build the largest pharmaceutical R&D institute in China
2010 Joseph Jimenez was named CEO
FDA approved Gilenya as the first oral treatment for relapsing-remitting multiple sclerosis
2011 Vaccines and medicines from Novartis reach an estimated $1 billion patients
Ranked No. 1 among pharmaceutical companies in Fortune magazine’s “World’s Most Admired Companies” survey
2012 Novartis to start construction of new biotechnology facility in Singapore with an investment of over $500 million
Source: Company documents.
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Novartis: Leading a Global Enterprise 413-096
Exhibit 3 Divestments and Acquisitions, 1992–2012
Acquisitions Divestments Other 1992 Systemix (genetics science
company)
1994 Gerber (baby food producer), $3.7B
1995 Clariant (specialty chemicals) spun-off
1996 Azupharma (contract pharmaceutical developer)
MBT (construction chemicals) Novartis formed through merger of Ciba-Geigy and Sandoz Pharma divisions
1997 Merck Agro (crop protection business), $910M
Ciba non-pharmaceuticals businesses spun-off
First attempt U.S. listing (Delta) and integration of Stiftungen
1998 Roland
1999 Wasa sold to Barilla Alimentare ($315M), Eden sold to De-Vau- Ge Gesundkostwerk (undisclosed)
2000 Wesley Jessen VisionCare (contact lenses), $785M—made Ciba Vision the second-largest contact-lens company in the world
Syngenta (agribusiness) formed when Novartis and AstraZeneca PLC combined agricultural chemical business
2001 Roche (21.3%) (pharma)
2002 Roche (11.4%); Lek (generics), $900M
Wander AG (health foods)
2003 Unification of all generics operations into Sandoz
2004 Roche (0.6%); Sabex and Durascan; BMS medical nutrition
2005 Hexal; Eon Labs (generics); BMS over-the-counter
Nutrition & Santé (dietetics and organic foods) sold to ABN AMRO Capital France ($260M)
2006 Chiron (biotech firm), $5.4B Entry into human vaccines through Chiron acquisition
2007 Medical Nutrition business; Gerber baby foods sold to Nestlé ($5.5B)
2008 Speedel (pharmaceuticals), $880M
2009 Ebewe (injectables), $1.2B
2010 Merger with Alcon (eye care)
2012 Fougera Pharma for $1.25B
Source: Compiled from company documents.
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413-096 Novartis: Leading a Global Enterprise
Exhibit 4 Novartis Business Divisions
Division Name Description Pharmaceutical Products concentrated in major therapeutic areas including: primary care
(hypertension, metabolism, respiratory); established medicines (oncology, including hematology), specialty (neuroscience, ophthalmics, integrated hospital care, and critical care.) The portfolio included more than 40 key marketed products, many of which were leaders in their respective therapeutic areas. In 2011, the division received a total of 15 approvals in the United States, Europe and Japan. The product development pipeline had 138 projects in various stages of clinical development, including potential new products as well as potential new indications or formulations for existing products.
Alcon Alcon was the global leader in eye care with a breadth of product offerings in
surgical, ophthalmic pharmaceuticals and vision care, serving the full life cycle of patient needs across eye diseases and vision conditions.
Sandoz Sandoz develops, produces and markets approximately 1 000 compounds
across all major therapeutic areas, as well as biopharmaceuticals, active substances and intermediates. Its operations span five continents, and it markets products in about 130 countries. In addition to its retail generics business, Sandoz also operates anti-infectives and biopharmaceuticals and oncology injectables businesses, where it has a strong leadership position.
Consumer Health Novartis OTC (Over-the-Counter) was a world leader in the research,
development, production and marketing of self-care products designed for in- home treatment of medical conditions and ailments. The division had a portfolio of cough, cold, respiratory disease treatments, digestive health solutions and pain management medication, as well as skin care products, smoking- cessation therapies and mineral supplements. Novartis Animal Health was a leader in developing new and better ways to prevent and treat diseases in pets, farm animals and cultivated fish.
Vaccines and Diagnostics The Novartis Vaccines and Diagnostics Division provided more than 20
vaccines to prevent viral and bacterial diseases, as well as sophisticated instruments, assays and software to protect the blood supply from infectious diseases such as HIV and Hepatitis. The division consisted of two businesses—Novartis Vaccines and Novartis Diagnostics.
Source: Company documents.
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Novartis: Leading a Global Enterprise 413-096
Exhibit 5 Novartis Share Price vs. Indices, January 1997–January 2013
Source: Thomson Reuters Datastream, accessed May 7, 2013.
50
100
150
200
250
300
Ja nu
ar y
31 , 1
99 7
= 10
Novartis Relative Stock Price Performance January 1997 – January 2013
WORLD PHARMA INDEX NOVARTIS NOVARTIS ADR
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413-096 Novartis: Leading a Global Enterprise
Exhibit 6 Organizational Structure, January 2013
Source: Company documents. Information as of January 2013.
Audit & Compliance
Peter Elam
Corporate Secretary
Dr. Charlotte Pamer-Wieser
Human Resources
Dr. Jurgen Brokatzky-Geiger
General Counsel
Dr. Felix Ehrat
Strategic Planning & External Affairs
N.N.
CFO
Jon Symonds
Group Communications
Michele Galan
Chairman Audit & Compliance Committee
Prof. Srikant Datar
Group QA
Dr. Erwin Vanhaecke
Chairman Board of Directors
Prof. Ulrich Lehner
CEO
Joseph Jimenez
Chairman’s Office
Dr. Matthias Leuenberger
NIBR
Dr. Mark Fishman
Pharma
David Epstein
Sandoz
Jeff George
V&D
Dr. Andrin Oswald
Chief Compliance Officer
Dr. Peter Kornicker
ECN Members
Alcon
Kevin Buehler
OTC
Brian McNamara
Animal Health
Dr. George Gunn
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Novartis: Leading a Global Enterprise 413-096
Exhibit 7 Executive Committee, Select Years
Position 1997 2002 2007 2012 CEO, Novartis AG Daniel Vasella, M.D Daniel Vasella, M.D Daniel Vasella, M.D Joseph Jimenez
CFO, Novartis AG Raymund Breu, Ph.D Raymund Breu, Ph.D Raymund Breu, Ph.D. Jonathan Symonds
Head, Pharma Thomas Ebeling Joseph Jimenez David Epstein
Head, Consumer Health Paul Choffat, J.D Thomas Ebeling Brian McNamara
Head, Sandoz Andreas Rummelt, Ph.D. Jeff George
Head, Vaccines and Diagnostics
Joerg Reinhardt, Ph.D. Andrin Oswald
Head, Research Mark C. Fishman, M.D. (Pharma)
Mark C. Fishman, M.D.(biomedical)
Mark C. Fishman
Head, Human Resources Norman C. Walker Juergen Brokatzky-Geiger, Ph.D
Juergen Brokatzky- Geiger
Head, Legal and General Affairs
Alexandre Jetzer Urs Bärlocher J.D. Felix Ehrat, Ph.D
Head, Corporate Affairs Thomas Wellauer, Ph.D.
Head, Strategic Planning Gilbert Wenzel
Source: Company documents.
Exhibit 8 Novartis Board of Directors, 2012
Daniel Vasella, M.D.——Chairman
Ulrich Lehner, Ph.D.——Vice Chairman (since 2002) Former CEO, A.G.
Dimitri Azar, M.D., MBA (since 2012) Dean of the College of Medicine and Professor of Ophthalmology, Bioengineering and Pharmacology at the University of Illinois at Chicago.
William Brody, M.D., Ph.D. (since 2009) President of the Salk Institute for Biological Studies, La Jolla, California, and former president of Johns Hopkins.
Srikant Datar, Ph.D (since 2003) Professor at Harvard Business School.
Ann Fudge (since 2008) Former CEO of Young and Rubicam.
Pierre Landolt, Ph.D (since 1996) Chair of the Sandoz Family Foundation.
Enrico Vanni, Ph.D (since 2011) Former McKinsey Managing Partner.
Andreas von Planta, Ph.D (since 2006) Vice Chairman of Holcim Ltd. and of the Schweizerische National- Versicherungs-Gesellschaft A.G.
Dr. Ing. Wendelin Wiedeking (since 2003) Former CEO, Porsche, GmbH.
Margorie Mun Tak Yang (since 2008) Chairman of Esquel Group, Hong Kong, China.
Rolf M. Zinkernagel, M.D. (since 1999) University of Zurich Medical School Faculty and Nobel Prize Winner.
Source: Company documents.
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Novartis: Leading a Global Enterprise 413-096
Exhibit 10 Average Annual Peak Sales of First Launched Products, 2007–2011 (in $ billions)
Source: Company documents.
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413-096 Novartis: Leading a Global Enterprise
Endnotes
1 “FTC Clears Novartis Merger, Creating the World’s Leading Life Sciences Company,” PR Newswire December 17, 1996, via Factiva, accessed March 2013. 2 McKinsey & Company, “An interview with Daniel Vasella,” September 2012, http://www.mckinsey.com/features/leading_in_the_21st_century/daniel_vasella, accessed March 2013. 3 Srikant Datar and Carin-Isabel Knoop, “Novartis (A): Being a Global Leader,” HBS No. 198-041. 4 Datar and Knoop. 5 Datar and Knoop. 6 Joseph Brown, “Concentrated focus (Novartis),” Med Ad News, September 1, 2000, via Factiva, accessed March 2013. 7 Brown. 8 “Agrochemical deal planted,” CNN Money, December 2, 1999, http://money.cnn.com/1999/12/02/europe/drugdeal/, accessed January 2013. 9 Brown. 10 Brown. 11 Brown. 12 Brown. 13 Kerry Capell, “Novartis: Radically Remaking Its Drug Business,” Bloomberg BusinessWeek, June 11, 2009, http://www.businessweek.com/magazine/content/09_25/b4136030131343.htm, accessed March 2013. 14 Capell. 15 Jeanne Whalen, “Novartis’s Big Experiment—Former Professor Reinvents Process for Making Drug Discoveries,” The Wall Street Journal, p. 4, January 19, 2005, via Factiva, accessed January 4, 2013. 16 Brown. 17 Moore. 18 Carey Sargent, “Novartis Can Stand Alone On Portfolio, Sales Strength,” Dow Jones International News, March 27, 2002, via Factiva, accessed March 22, 2013. 19 Nicolai Ouroussoff, “Many Hands, One Vision,” New York Times, December 23, 2009, http://www.nytimes.com/2009/12/27/arts/design/27novartis.html?pagewanted=all&_r=0, accessed April 2013. 20 Ouroussoff. 21 Haig Simonian, “Sandoz chief has no misgivings over Hexal,”Financial Times, April 13, 2005, http://search.proquest.com, accessed March 5, 2013. 22 “Novartis: Downgrade to Peer Perform after Alcon Acquisition,” Bear Stearns, April 8, 2008, available via Thomson ONE, accessed March 2013. 23 “Novartis: Downgrade to Peer Perform after Alcon Acquisition,” Bear Stearns, April 8, 2008. 24 McKinsey & Company, “An interview with Daniel Vasella,” September 2012, http://www.mckinsey.com/features/leading_in_the_21st_century/daniel_vasella, accessed March 4, 2013. 25 Geoff Colvin, “Novartis’s pathway to business longevity,” Fortune Magazine, March 21, 2013. 26 Colvin, “Novartis’s pathway to business longevity.” 27 Colvin, “Novartis’s pathway to business longevity.” 28 Colvin, “Novartis’s pathway to business longevity.” 29 Colvin, “Novartis’s pathway to business longevity.”
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Group Income Statement

Novartis: Leading a Global Enterprise 413-096
 a British CFO, and a Swiss general counsel and a German human resource head. Its six businesses were led by four Americans, one Swiss and one Brit. The Novartis board, once comprised of 12 Swiss members, one American and one German, had also globalized, and now included five Swiss, two Germans, two Americans, a Chinese woman, and one member each born in India and Lebanon. (See Exhibit 8 for 2012 board composition.)
Leadership Challenges
In terms of developing global leaders, Vasella noted, “Hard skills are easier to transmit, while soft skills are much more difficult to teach. You can teach concepts, but you can’t teach experiences. To be a good leader, you need to be intelligent, a conceptual thinker, ambitious, and take pleasure in building organizations.” He continued:
Those qualities need to be balanced by skepticism—recognition that not everyone wants you to succeed and that bad things will happen. If I look at the reasons leaders fail, it’s usually the soft factors, such as failing to resist seduction. I talk to my team about the temptations that come with leadership—sexual enticement, money, or praise. You need to be aware of your vulnerabilities in order to resist seduction and keep your integrity.24
“Today’s leaders must understand what society needs, values and will pay for,” Vasella continued, “and have the courage to stand up for it even if unpopular. They need courage to make mistakes and not think their heads will be cut off. Leaders need to avoid taking shortsighted actions. I worry most about pressures people feel from the stock market to take short-term actions like portfolio management and restructuring to pull the white rabbit out of the hat.”
Breu added, “New leaders should not imitate the past. They have to think very differently about the next ten years. How do you anticipate what will happen and place your bets? There will be changes to the way business units operate, to the portfolio and the company’s global footprint. In my time the challenge was getting larger in the U.S. Now the opportunities are in Asia, Brazil and potentially in Africa. Novartis’ culture has become very international. From two Swiss companies we became a global healthcare leader. In 1996 people would have said: ‘As an American, I have no chance of being CEO of Novartis.’ That has changed.”
When Vasella concluded his 14 years as CEO, he said he left the company with strong leadership, excellent financial results, a diversified set of healthy businesses, and a full pipeline of new products. That year 910 million people benefited from Novartis products. He noted:
We came out of a diversified business, and divested everything except healthcare. By expanding there, we became stronger and more diversified. Now there is a different evolution. Companies which were once on the top of the industry have fallen, so the analysts are saying companies should diversify. Competitors who once said generics were incompatible with pharmaceuticals, are suddenly entering generics.
After 25 years with Novartis, including three additional years as board chair, Vasella announced he would step down at the 2013 AGM. With the board’s support, he persuaded Reinhardt to return to Novartis as non-executive chair of the board. Vasella agreed to refrain from competing with Novartis for six years in exchange for CHF 12 million per annum, which he committed to donate entirely for philanthropy. Nevertheless, the disclosure set off a political firestorm in Switzerland, which was in the midst of a referendum on the Minder Initiative supported by activist shareholders aimed at limiting CEO pay. One week before the AGM, Vasella announced that he decided to forgo any
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413-096 Novartis: Leading a Global Enterprise
payments related to his non-compete agreement while the Board cancelled the non-compete clause of his contract. Five days later the Minder Initiative passed.
Joe Jimenez’s New Era
On February 1, 2010 Jimenez became the first American to lead a Swiss pharmaceutical company. He was not a physician by training and had spent most of his career in consumer goods. At age 37, he headed up H. J. Heinz’s North American operations, and was head of its European operations from before joining Novartis. He recalled, “When Dan asked me to run pharmaceuticals, I said, ‘You’re kidding, somebody with no pharmaceutical background, not a scientist, a researcher, or a medic?’ He replied, ‘We have lots of good medics and good scientists, but don’t have someone who can look outside and see what is happening in the world and position the division for future growth.’”
Just as Moret had bet on him, Vasella bet on Jimenez. “Not being a physician or a scientist and running a science-based organization is an interesting challenge,” Jimenez conceded.
You have to know enough about the science to know whom to listen to. My advice is, play to your strengths. I could look outside this industry, understand how the world was changing, and position the company to take advantage of it. Coming from outside has its advantages, as you don’t get caught up in the internal way of thinking.25
As Jimenez looked ahead to his challenges, he saw several imperatives: 1) addressing the rapid changes in global health systems; 2) sustaining research excellence; 3) building a balanced, vibrant health care portfolio; 4) expanding in emerging markets; and, 5) developing global leaders.
Meeting the Challenges of Global Health Systems In the U.S., the Affordable Care Act was expected to put cost pressure on healthcare providers,
including drug manufacturers. In Europe, highly stressed governments sought ways to reduce health care and drug payments.26 “Patients need innovative pharmaceuticals, but also low-cost options,” Jimenez said, observing that this played to Novartis’ strengths:
With financially troubled healthcare systems around the world, just offering innovative pharmaceuticals at $60,000 to $80,000 per year is a risk profile we don’t want to be in. Due to the breadth of our healthcare portfolio, less than 55% of our sales are reimbursed by public agencies. We see significant opportunities in healthcare starting with the patient to offer more than just pharmaceuticals. We can also use our R&D expertise to excel in generics and take advantage of the volume growth. There are hundreds of millions of patients around the world who need Sandoz generics with very high-quality but low-cost.
Jimenez said the future for pharmaceuticals was in moving from the science of medicine to the art of healing. “Everything must start with the patient,” he said. “Our traditional business model was a transaction—selling pills to physicians. Today payers and physicians are insisting on positive outcomes for patients. We need leaders with skills who focus on holistically helping patients with programs, technology, and services to help physicians deliver positive patient outcomes.”
As global head of Novartis Pharmaceuticals, Epstein anticipated major shifts in the pharmaceutical industry. “In the past we were just selling pills. Today you have to understand the patient’s journey from diagnosis through treatment of their disease,” he said. “Without that understanding, you don’t have the insights to develop a sophisticated strategy. In the oncology
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Novartis: Leading a Global Enterprise 413-096
business, we worked together on the same team with the same metrics in commercial and development. Together we talked to customers, developed strategy, and made smarter decisions enabling us to leapfrog the competition with the next clinical trial, drug combination, or new patient segment. Now we’re using that approach for the entire pharmaceutical business.”
Jimenez added, “The global financial crisis has put tremendous pressure on national governments to constrain healthcare spending. These days we have to partner with governments to demonstrate the value of patient outcomes. In oncology, this means developing companion diagnostics to provide 100% certainty that patients will respond to a drug, thereby avoiding the waste of ineffective drugs.”
Sustaining Research Excellence
While spending $9 billion per year on Group R&D (including an amount for pharma research which totaled 20% of pharma sales), Novartis considered research productivity critical to its future. Jimenez’s attitude was to invest where the talent was. “We build our research centers where the scientists are—in Cambridge, Basel, and Shanghai,” he explained. He and Fishman planned to expand on the pathways approach to drug discovery by understanding the molecular pathway of diseases, often rare diseases with small but homogeneous patient populations. “We develop a drug that interrupts that pathway, and then expand into other disease areas impacted by the same pathway,” he noted. See Exhibit 9 for Novartis’ pipeline.
Jimenez was bullish about two therapeutic areas, oncology and regenerative medicine. “The sequencing of the human genome has created a wealth of data that will allow discovery of new drugs never before possible,” he said. He was also betting on regenerative medicine, using technology to tackle problems of muscle, sight and hearing loss.27 “Mining bioinformatics data is essential in understanding specific mutations leading to cancer,” Jimenez noted.28 “This requires melding medical, scientific, and information technologies to create medical advancements.”29 Through all the shifts Novartis expected to maintain its high R&D investment (see Exhibit 10).
Building a Balanced, Vibrant Health Care Company
One of Jimenez’s concerns was getting Novartis’ other health care businesses up to critical mass so they would be full contributors to the company’s revenues and profits, giving counterbalance to its pharmaceutical business. In examining them, he noted that Alcon’s industry leadership gave it that mass in eye care, and Sandoz’s recent expansion brought it just to critical mass in generics. However, OTC, vaccines and diagnostics, and animal health were too small to sustain required investments while contributing significant bottom-line profits. He said:
There is a scale benefit that comes from multiple divisions that permits longer-term investment decisions. We let businesses invest through the cycle, and use good years in one division to permit another division to invest. There are also costs to being part of Novartis. Quality standards that make sense for pharmaceuticals are being imposed on smaller divisions in ways that wouldn’t happen if they were independent. Last year’s quality problems were a painful reminder that Novartis must set its standards at the most demanding level, which is expensive. In Sandoz and OTC, this accounts for a disproportionate amount of their profitability. The challenge is turning superior quality in these businesses into a competitive advantage over smaller competitors.
We assess each unit during the annual strategy cycle to ensure it has a viable strategy to become a leader in its field and create net present value. We have the financial ability to invest deeply in innovation and apply that innovation across all the divisions. Each
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413-096 Novartis: Leading a Global Enterprise
division has also benefited from each other’s talent, especially the smaller units that have access to pharmaceutical capabilities.
Novartis’ vaccine business was the most volatile in the portfolio. In 2009 the division was $500 million below target, but the following year it hit high profit margins with the first vaccine for H1N1 for swine flu. Recalled business head Andrin Oswald: “By hiring 1,000 people, we were first to ship the vaccine. This is great example of Novartis doing extraordinary things in a crisis.“ Unfortunately, the pandemic took management’s focus off the core vaccine business. “When the panic was over, orders for the H1N1 vaccine fell close to zero, profits disappeared, and the business went into a loss. During the crisis it was hard to focus on our core strategy, as demand for other vaccines dropped, and quality issues arose. This might not have happened had we not focused on the pandemic,” Oswald said. However, in 2012 three new vaccines were approved, an industry first.
While Jimenez saw the potential for generics to expand Novartis’ reach, especially in emerging markets, he acknowledged the challenges of competing in generics. On average, the cost of a generic drug was 80% to 85% lower than the brand-name product; generic drugs saved American consumers alone $150 billion per year. Although profit margins were lower as limited barriers to entry meant more competitors and lower prices, production costs were rising because the FDA required generic manufacturers to pass the same quality standards as those for brand-name drugs.
When George took over Sandoz in late 2008, it was considered Novartis’ step-child, with revenue growth only 1% and costs up 10%. The culture was considered slow, complacent, and weak commercially. George replaced half of Sandoz’s top 200 people and focused on near-term performance. The first three years produced annual revenue growth of 12% and profit increases averaging 17%. In 2012 new competition for its best-selling product and added quality costs drove down 2012 revenues and profit margins, in spite of $2 billion in cost savings between 2009 and 2012. Meanwhile, George shifted Sandoz’s strategy to specialty generics such as biosimilars, oncology, ophthalmology and dermatology where profit margins were higher. He noted, “Each year we face high single-digit price erosion which must be offset with higher volumes. We need to recreate two- thirds of annual income to stay even while aggressively cutting costs.”
Expanding in Emerging Markets
With slower growth in the U.S. and Europe, Jimenez saw great opportunities in emerging markets. “China grew 24% last year,” he said, “because the Chinese government made a massive commitment to improving health care. The Russian government is dedicated to improving healthcare access to reverse its population decline. Africa is the next emerging market so we are building infrastructure in sub-Saharan Africa. Nigeria and Kenya are growing 6% to 7% per year.”
To accelerate revenues in select high-growth emerging markets, Novartis shifted to a single country organization in 2008 under Global Emerging Markets (GEM). While the new organization worked well for pharmaceuticals, lower margin businesses like generics found it difficult to get the attention of country management. According to George, “We found that the growth rate in GEM markets was well below what the generics business generated with its own country managers.” In 2012 the GEM organization was disbanded with country responsibilities returned to the divisions.
An experiment in China with a single country management was much more successful. The large size of the market enabled the Chinese country organization to staff the divisions at appropriate levels with clear focus on their respective business. “We feel this structure is working well under centralized management in China,” said George. “We are realizing growth exceeding 20%.”
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Novartis: Leading a Global Enterprise 413-096
Nevertheless, Oswald pointed out how challenging it was to reconcile Novartis’ high cost base with local employee expectations and immature markets. In 2011 Novartis purchased a Chinese vaccine company. Within two years of becoming part of Novartis, its costs doubled, as the 600-employee company had no HR or IT systems. “We brought in the Novartis systems and applied our strict business practices,” Oswald noted. “It’s hard to compete against local companies with Novartis rules.”
Patent protection was also a challenge. In early 2013 India’s Supreme Court denied Novartis’ Gleevec patent, concluding a seven-year process that began in 2006. The court’s decision was a major win for local generic makers like Cipla and Natco Pharma, which sold generic versions of Gleevec for 10% of Novartis’s price. India managing director Ranjit Shahani, said the company would now be cautious about investing in R&D activities in India. Industry leaders worried the Gleevec decision could cause the global patent system to unravel.
Jimenez was also considering whether Novartis had the right organizational structure for its global business: each of its six businesses had complete organizations in every country. This gave businesses greater autonomy and increased focus on their customers; however, the high cost of duplicative country and regional staffs was an impediment to profitability. While the structure seemed fully justified for the giant pharmaceutical business, it raised questions for the other units.
Finally, Jimenez questioned whether the back office structures in each country should be managed centrally, leaving front-line sales and marketing to the six divisions. Although experiments with centralized systems had resulted in higher costs, Jimenez was uncertain whether this was the result of the principle of centralized systems or ineffective execution.
Developing Global Leaders
Jimenez believed Novartis faced a major challenge in building its global leadership team for the future. In spite of its successful evolution from Swiss-dominated management, the shortage of leaders from emerging markets concerned him. “Two years ago we launched a project called “Lead” to take 20 high-potential emerging market leaders, and give them 18-month assignments working with the executive committee and on action projects,” he noted. “They come to Basel to learn our culture, and go back to their host country to function as local and global leaders.”
Reflecting on what was required to develop its cadre of global leaders, Jimenez felt they had to develop themselves along three dimensions: leading self, leading team, and leading the business. “When we assess Novartis leaders on self, teams, and business, self is the weakest,” he said.
We are injecting this leadership framework into our 360s review process from the entry level all the way to me. Leading self requires knowing your strengths and weaknesses, backstopping your weaknesses, and focusing your time on what’s most important. We have leaders who are great in motivating their teams, and great strategists who guide their businesses in very thoughtful ways, but struggle in leading themselves. By assessing people on those elements, we identify how to help them. For today’s leaders in such a complex world, leading self is an important aspect where we cannot afford outages. In the past, leadership was about execution. In the next 10 years leading self will be the most important for success.
Jimenez cited an example of why leading self matters. “We had an American who failed as a global leader because he thought he needed to spend his time and energy in the U.S. Instead, he should have been driving our smaller, emerging markets in other parts of the world. This requires an awareness of and respect for cultural differences and an appreciation of the potential of other
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413-096 Novartis: Leading a Global Enterprise
countries. I’ve seen many people who aren’t global leaders because they can’t think beyond their home country. All decisions are steeped in that dominant culture.
Jimenez believed that physically living in different countries was critically important for the globalization of a leader. “When you take leaders out of their U.S. comfort zone and put them in a country like China or India,” he explained, “where they have to figure out how to buy groceries, go to the doctor, and exist in another country, we see powerful transformations in their self-awareness and respect for other cultures. As a result, they figure out how to grow their business using different business models than the ones they are used to.”
Brokatzky-Geiger noted that Novartis employed a high touch approach to its 360 review process. “We work with external professionals to interview executives, their peers and direct reports and have open discussions with them. The interviewers can ask questions that internal people cannot, giving us a better picture of their capabilities, often with very descriptive examples,” he explained. “Our accelerated development program for developing global leaders identifies top talent and sends them to areas where they haven’t worked before.” He added:
Sometimes we move people into commercial, development, or general manager roles. We use this targeted approach because everyone brings something different to the table. Everyone is missing some element required to be an outstanding global leader. In addition to developing expertise, global leaders need to be self-aware and understand their impact on their organizations, take feedback, and change their behavior when needed.
The Future
Looking to the future, Jimenez was clearly focused on his priorities: innovation, growth, productivity and organizational health. “My goal is to put us on a growth trajectory that is sustainable long after I am gone,” he said. He set up a special meeting with his executive committee to sharpen the focus on these goals and become the world’s leading healthcare company.
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Novartis: Leading a Global Enterprise 413-096
Exhibit 1a Group Income Statement, 1996, 2002, 2006, and 2010 to 2012
1996 2002 2006 2010 2011 2012 Net sales $27,060 $20,887 $34,393 $50,624 $58,566 $56,673 Operating income 4,317 5,092 7,681 11,526 10,998 11,511 Net income 1,721 4,725 7,175 9,969 9,245 9,618
Basic earnings per share $1.84 $2.28 $4.28 $3.83 $3.93
Exhibit 1b Healthcase Portfolio Overview, 2012
Source: Company documents.

Strengthening Healthcare Portfolio

413-096 Novartis: Leading a Global Enterprise
year alliance with the World Health Organization (WHO) to provide Coartem, Novartis’ breakthrough malaria medicine, without profit for use by public health systems in developing countries. Novartis provided Coartem for $1.57 per treatment and WHO distributed it through governments of malaria-endemic countries. Coartem obtained regulatory approval from three countries in 1999 and from the FDA in 2009. By 2013 Novartis had provided 500 million treatments without profit, making it one of the largest access-to-medicine programs.
Globalizing Novartis Research
Vasella’s boldest move came in 2002, when he abandoned the traditional drug-development model, declaring Novartis would only investigate diseases for which new drugs were desperately needed and where there were a solid scientific basis or hypothesis of the mechanisms (genetic and/or pathways) leading to the target illnesses. While other CEOs saw the pursuit of rare diseases as commercial suicide, Vasella believed many of the illnesses shared genetic underpinnings with more common ailments.14
Historically, both Sandoz and Ciba leaders felt they could attract the best scientists in the world to work in Basel. In contrast, Vasella felt the company needed to be where the talent pool was located and that Novartis needed to attract the top scientists in the U.S. Consequently, he shifted Novartis’s global research headquarters to the U.S. by establishing the Novartis Institutes for Biomedical Research (NIBR) in Cambridge, MA near Harvard University and MIT. While the Basel research site was maintained, the company closed its research center in New Jersey, transferring key scientists to Cambridge. The original investment was $1 billion.
To head NIBR, Vasella recruited Mark Fishman, M.D., chief of cardiology at Massachusetts General Hospital, a geneticist and top scientist. “We needed an M.D. with a modern approach to research with vast knowledge of molecular biology and genetics, and with broad clinical experience,” Vasella explained. His decisions set off a firestorm in Basel. Concerns were voiced about “abandoning Basel” and hiring an American academic medical scientist without industry experience.
Fishman recalled, “The original idea was actually to have a research site in the Boston-Cambridge area, but I thought it had to be the headquarters for research. You can’t change an organization by modifying it from within. Second, research could not be part of pharma. It had to be discovery- driven, not financially-driven by marketing as most pharmaceutical companies were.”
Vasella agreed on both points, having Fishman report directly to him rather than Ebeling. This also led to internal criticism because the pharmaceutical group felt strongly it had to control its own research. “Separating research out,” Vasella said, “allowed me to protect the investment; otherwise, people start to cut it due to budgetary pressures.”
NIBR’s mission was to discover innovative new drugs that would change the practice of medicine. Traditionally, drug researchers discovered medicines by bombarding an illness with a variety of chemicals until they hit a combination that treated it. A research strategy based on molecular pathways, by contrast, zeroed in on the exact molecular mechanisms that caused a disease.15 Fishman cancelled 30% of research projects to shift the focus to rare diseases. “First, we have to understand the unmet need,” he explained, “and then the mechanism and the path of physiology in order to make a medicine.”
Fishman also changed the way Novartis selected research projects and the kind of scientists it hired. While Fishman saw early progress with his new molecular pathways-focused methods, he noted “the hostility from the old guard.” NIBR hired 1,000 people in its first year. “The few who came
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Novartis: Leading a Global Enterprise 413-096
from Basel were very valuable in terms of forming liaisons,” Fishman noted. By 2012 NIBR had 10 research institutes around the world with approximately 6,000 scientists. As part of this growth, Novartis committed to invest $1 billion in a new research center in Shanghai, China, making it the largest research center in China. “Having a Chinese research institute has helped the commercial groups a lot,” said Fishman, “because it is a vote of confidence in the country, and the government loves having us there.”
In April 2012, Fishman joined Governor of Massachusetts Deval Patrick and other local notables to break ground on a new 550,000 square foot campus of lab, office, and retail space across the street from the NIBR headquarters—a $600 million expansion.
Globalizing the Investor Base
With most of its stock held by Swiss institutions, Vasella and Breu decided Novartis needed to develop a global shareholder base. They believed the discipline of listing on the New York Stock Exchange (NYSE) would be beneficial. Consequently, in May 2000 Novartis listed its stock on NYSE, with a simplified share structure and $2.5 billion share-repurchase program.16 In 2003 Novartis began reporting in U.S. dollars, initially reconciling results between U.S. and international GAAP.
“We began thinking about U.S. stock listing back in 1990,” Breu said, “when we realized that our main competition was in New Jersey, not across the Rhine. To attract the best talent, we knew we would have to play by U.S. rules.” Some security analysts saw the U.S. listing as a gateway to a major acquisition or merger enabling Novartis to strengthen its U.S. position. In 1999 it approached both Monsanto Co. and American Home Products Corp. about possible transactions.17 Other observers felt Novartis would be better off alone, questioning whether it needed a big acquisition with its solid pipeline of upcoming drugs.18
Recasting Basel
In 2001 Vasella launched a plan to transform its Basel headquarters from a rundown chemical complex into a modern state-of-the-art campus designed by world-famous architects such as Frank Gehry, Rafael Moneo, and Alvaro Siza. Many buildings were demolished, except the 1939 headquarters. New facilities were designed to improve communication between employees and facilitate their daily lives by providing grocery shopping, banking services and so on. Office floor layouts encouraged cross-disciplinary interaction, while beautiful parks and courtyards provided space for quiet reflection. To implement its new campus design, Novartis purchased adjacent land from the city of Basel and closed a street that connected with French border control. Vasella noted, “We put 100 million Swiss francs on the table and the government agreed.”19 By 2012 10 research and office buildings were completed, with seven additional buildings under construction.20
Strengthening Novartis’ Healthcare Portfolio
Also in 2000, Novartis began broadening its healthcare portfolio, expanding its subscale generics business by acquiring BASF Pharma’s European business, U.S.-based Apotheccon and Germany’s Grandis. Two years later, it bought Slovenia’s Lek Pharmaceuticals to gain a presence in Central and Eastern Europe. Other acquisitions included Sabex and Durascan, Astra-Zeneca’s generic company.
In 2004 Novartis united its global generics operations in a new division under the Sandoz name, mothballed since the merger. The following year it acquired Germany’s Hexal and its U.S. affiliate, Eon Labs. Although some analysts had misgivings about the $8.3 billion price tag, Vasella felt it was
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413-096 Novartis: Leading a Global Enterprise
inevitable that tighter healthcare budgets would boost generics.21 Sandoz headquarters was relocated to Hexal’s headquarters outside Munich, Germany, to separate it clearly from the pharma business.
In 2006 Novartis acquired the remaining 58% of California-based Chiron, having purchased 42% in the mid-1990s. Chiron’s vaccine business with more than 30 vaccines was the fifth largest vaccine company. Novartis hoped new technologies and a shake-out in vaccines would transform it from a low-growth, low-price business. The following year Novartis disposed of its remaining non- healthcare assets, selling its medical nutrition and Gerber baby food businesses to Nestlé.
Novartis made its biggest bet ever in 2008, when it agreed to acquire Alcon eye care from Nestlé for an amount which ultimately totaled $52 billion. Analysts were displeased. As one noted, “We struggle to see how acquiring a market leader at top multiples can create shareholder value.”22 Another opined, “This transaction annihilates Novartis’s key attraction for investors: undervalued cash generation.”23
“Although security analysts were advocating that Novartis be a pure pharmaceutical company,” Breu explained, “we decided to invest in generic drugs, consumer health, vaccines and eye care to reduce exposure to pharmaceutical pricing pressures. From a margin standpoint, acquiring vaccines was a disaster, but we believed it had great long-term prospects. We’re growing the company, not improving margins by cutting R&D and marketing. Our goal is to maximize net present value, not increase the short-term stock price.”
Between 2000 and 2012, price-to-earnings ratios for the pharmaceutical industry dropped from 25 times earnings to 10 times, as analysts worried about R&D productivity and pricing power, which had shifted to buyers of healthcare (see Exhibit 5 for stock price information). Against the industry trend, Novartis increased investments in R&D and marketing. Breu noted, “We needed to invest to make Novartis ‘the best-in-class company.’”
Upgrading Executive Leadership
Throughout his 14 years as CEO, Vasella made continual changes to his executive team to ensure Novartis had the right leaders in place as the company expanded. In 2006 American Joe Jimenez was hired from H. J. Heinz as global head of consumer health, pharmaceuticals development head Joerg Reinhardt was named head of vaccines and diagnostics following the completion of the Chiron acquisition, and Andreas Rummelt, head of pharmaceutical operations, was asked to lead Sandoz.
The next year Vasella switched Jimenez’s and Ebeling’s positions: Jimenez became global head of pharmaceuticals as Ebeling took over consumer health. In late 2008 Vasella appointed Reinhardt as chief operating officer with all business reporting to him. He also promoted two young executives in their thirties to the executive committee, Swiss-born Andrin Oswald (37) as global head of vaccines and diagnostics and American Jeff George (35) as global head of generics. (See Exhibit 6 for an organization chart and Exhibit 7 for leadership changes over time).
At the start of 2010 the Novartis board accepted Vasella’s recommendation to name Jimenez his successor as CEO. Subsequently, Reinhardt left to become head of Bayer Healthcare. David Epstein, who had run oncology and specialty medicines in pharmaceuticals, succeeded Jimenez as global head of pharmaceuticals. Breu retired as CFO and was replaced by Jon Symonds, who came from Goldman Sachs and AstraZeneca.
With these appointments Novartis completed its transition from the Swiss-dominated leadership to a multi-national team at the top. The new executive committee had an American CEO and head of
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From Life Sciences to Healthcare

Regrouping
By 1998 Novartis results were disappointing, hurt by below par pharmaceutical sales and the Swiss franc’s appreciation. Moreover, Novartis was losing ground in the U.S., the largest and most profitable pharmaceutical market, while U.S. competitors were making major gains. With only a few new drugs in the 1999 pipeline, analysts observed that Novartis risked falling further behind U.S. competitors and should consider a large acquisition or merger.
Instead, Novartis doubled down on R&D. As a result of increased investment, the company was able to accelerate a large pipeline of products in late-stage clinical development, many of which came from Ciba’s labs. By the end of 1999, Novartis had 50 projects in clinical development—23 in Phase III clinical trials, 24 in Phase I and II clinical trials, and three in registration.6 Global Pharmaceuticals Head David Epstein noted: “We launched a new drug every 100 days from 2000 to 2003. Most companies are happy to launch one product per year, let alone three or four.”7
Global Bets for a New Century
At the start of the new century, Vasella decided on several strategic initiatives: 1) shift the focus from life sciences to healthcare, 2) invest in businesses not attractive to competitors, 3) globalize research, 4) globalize the investor base; and 5) transform headquarters to reflect the company’s global scope, innovation and care for its associates.
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Novartis: Leading a Global Enterprise 413-096
From Life Sciences to Healthcare
In 2000, Novartis decided to focus entirely on healthcare. It spun off and merged its agricultural business with the Anglo-Swedish firm AstraZeneca’s business to form a new company, Syngenta, with revenues of $8 billion and a market value of $12 billion, then the world’s largest agrochemical business.8
Also in 2000, the company reorganized its pharmaceutical business to focus on its strongest products, dividing it into primary care, specialty care, and mature products business units, providing each with greater autonomy. “We are aligning our pharmaceutical activities around franchises and strategic brands with a focused management structure,”9 Vasella said. “These changes provide entrepreneurial space, speed, and resources to our leaders.”10
Vasella changed pharmaceutical leadership, replacing Jerry Karabelas with Thomas Ebeling who ran consumer health, having joined Novartis from PepsiCo. Ebeling noted, “The new business unit leaders will have autonomy and clear accountability, with responsibility for managing their portfolios from research through market activities.”11 As a result of shifting marketing resources to key products, sales of the company’s top 10 products grew 12% in 1999.12
In 2001 Novartis purchased 20% of the voting shares of cross-town rival Roche. In 2002-03 it acquired additional shares, bringing its holdings to 32.7%, slightly below the level at which Swiss law required Novartis to make a tender offer for the company. Meanwhile, Roche’s two founding families, which held over 50% of voting shares, were bound together by an agreement prohibiting them to sell. Novartis’s moves were not well received by Roche management, in spite of Novartis’ commitment to be only a passive investor. In 2013 Novartis still retained its shares, with the power to block any change of Roche’s capital structure needed for a large transaction.
Beyond Blockbusters
In pharmaceuticals, Vasella challenged the firm to look beyond blockbusters by focusing on smaller patient populations or emerging market diseases. In 1990 a team of scientists began testing 400 molecules to find one targeting Chronic Myelogenous Leukemia (CML). After two years of testing, the team developed the molecule that became Gleevec. Referred to by many as a “miracle drug,” Gleevec targeted the genetic defect causing the malignancy. The market was small, with only 28,000 CML patients worldwide. Early animal tests hinted at some liver toxicity, and Ciba-Geigy had been hesitant to take risk on a potentially toxic drug. Listening to the complaints of Dr. Alex Matter, head of oncology research, during a hallway discussion, Vasella pushed for the start of clinical trials.
After seeing stunning results in just 31 patients in Phase I clinical trials, Vasella went to the labs to talk to the Gleevec team. There he learned that the project had effectively been shelved due to lack of funds to proceed with further clinical trials. Despite disagreements with some senior colleagues who were hesitant due to the small market for CML, Vasella decided to accelerate Gleevec’s development, telling them he wasn’t concerned with the high cost. In less than two years, U.S. Food and Drug Administration (FDA) approval was received in 2001 due to the FDA’s special “fast track” procedure for life saving cancer and AIDS drugs. Through 2013, Gleevec had proven effective against six other life-threatening diseases, validating Novartis’ early strategy.13 In 2012 Gleevec and its successor drug Tasigna generated $5.7 billion in sales worldwide, making it Novartis’ largest product.
Early in his tenure, Vasella committed to making the fight against leprosy and malaria a cornerstone of Novartis’ access-to-medicine programs providing all drugs for the treatment of leprosy worldwide free of charge. In 2001 he launched the Novartis Malaria Initiative, unveiling a 10-
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Leading a Global Enterprise

9-413-096
R E V : O C T O B E R 3 , 2 0 1 4
W I L L I A M W . G E O R G E
K R I S H N A G . P A L E P U
C A R I N – I S A B E L K N O O P
Novartis: Leading a Global Enterprise
How do you follow a legacy CEO? This is the hardest thing you could possibly encounter. Dan [Vasella] shaped the company, the portfolio, and the future of the company.
— Joe Jimenez, CEO
As the 2,688 attendees at the February 22, 2013 Novartis annual general meeting (AGM) filed out of the large assembly hall, 53-year-old Novartis CEO Joe Jimenez realized that the retirement of Daniel Vasella, MD as chair of the Novartis board meant the ball was entirely in his court. Since its formation 17 years earlier with the merger of Sandoz and Ciba-Geigy in 1996, Novartis had been led by Vasella, either as CEO, board chair or both. At the meeting vice chair Ulrich Lehner was elected interim chair to serve until August, 2013, when Joerg Reinhardt, former chief operating officer of Novartis and currently head of Bayer Healthcare, would return as chair of the Novartis board.
Vasella was elected honorary chair at the meeting, but would only attend board meetings as a guest and coach senior company executives without any other involvement. “I left the company with a good successor, a rich pipeline, a solid financial footing and a good top team,” Vasella said after the meeting. From its Basel, Switzerland headquarters Novartis leadership orchestrated 127,000 employees of 153 nationalities in 140 countries. With $56.7 billion in 2012 revenues and $9.6 billion in net income, Novartis ranked as one of the world’s largest and most profitable companies. (See Exhibits 1 for basic financials, 2 for milestones, and 3 for divestments and acquisitions.)
Jimenez, who succeeded Vasella as CEO in 2010, recognized that rapid changes in the global health care environment would create severe challenges for Novartis in the years ahead. “My greatest worry is taking a company that has been successful for a decade and a half and positioning it in today’s external environment,” he said. Among those challenges were changes in national health care systems, like the Affordable Care Act in the US, putting downward pressure on prices and changing the way companies got paid for their products from prices per pill to paying for patient outcomes, which no one had figured out how to measure precisely.
Jimenez was clear about his mandate as CEO: “My mission is turning us from a pharmaceutical company into a global healthcare company.” The pharmaceutical business provided 57% of sales and 66% of operating income, and dominated the culture. A survey of global executives conducted by
Professors William W. George and Krishna G. Palepu and Executive Director Carin-Isabel Knoop (Case Research & Writing Group) prepared this case. It was reviewed and approved before publication by a company designate. Funding for the development of this case was provided by Harvard Business School and not by the company. Professor George served on the board of Novartis from February 1999 through February 2009, and also led Novartis leadership seminars in 2010-11. HBS cases are developed solely as the basis for class discussion. Cases are not intended to serve as endorsements, sources of primary data, or illustrations of effective or ineffective management. Copyright © 2013, 2014 President and Fellows of Harvard College. To order copies or request permission to reproduce materials, call 1-800-545- 7685, write Harvard Business School Publishing, Boston, MA 02163, or go to www.hbsp.harvard.edu. This publication may not be digitized, photocopied, or otherwise reproduced, posted, or transmitted, without the permission of Harvard Business School.
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413-096 Novartis: Leading a Global Enterprise
Fortune Magazine ranked Novartis as the world’s most admired pharmaceutical company for the third consecutive year. It was best known for anti-hypertensive Diovan and its leukemia treatment Gleevec. “With financially troubled healthcare systems around the world, offering only innovative specialty pharmaceuticals would put us in a risk profile where we don’t want to be,” Jimenez said.
Reflecting on the company’s five other divisions—generic drugs, eye care products, over-the- counter medications (OTC), animal health, and vaccines and diagnostics—Jimenez worried that none of them alone was large enough to offset pressures on the pharmaceutical business (see Exhibit 4). Jimenez also was concerned that several of the company’s smaller units lacked the scale to operate as separate global units. He believed strongly in the global division structure with different business models, but was not comfortable with the infrastructure cost of duplicate functions. “If we could standardize our processes, we could free up resources to drop to the bottom line or reinvest in the business. Yet I fear taking away the autonomy of division management and in-country leadership. We’ve had knock-down, drag-out fights about this and still don’t have it resolved.”
In spite of its size and scope, the company had a long way to go to serve a high proportion of the world’s population, especially in rapidly growing developing countries like Brazil, China, India, and Russia. “We are working on developing global leaders from the fast-growing markets because that’s our biggest deficit,” Jimenez observed. “You look around our executive committee and there’s not one person from Brazil, China, or Russia. It’s not because we don’t look for them; it’s because we haven’t been able to develop them.”
Back in his office, Jimenez asked his assistant to put all these issues on the agenda for the next executive committee meeting to discuss with his top team.
The Birth of Novartis Born on December 23, 1996 from the merger of Sandoz and Ciba-Geigy, Novartis instantly became
one of the world’s leading life sciences companies. Former Ciba-Geigy chair Alex Krauer was elected to chair the new Novartis board. Krauer felt the two organizations were “perfectly matched in terms of professional skills, financial strengths and innovative capabilities to form a new company with tremendous growth potential.”1 The merger gave the two companies benefits of scale and extended their geographical reach. Recalled general counsel Urs Barlocher, “The old Swiss companies were export-oriented and went to countries with market potential, but were certainly not global.”
Daniel Vasella, a 42-year-old physician who has been head of Sandoz’s pharmaceutical business, was named CEO. After graduating with high honors from University of Bern, where he studied medicine and psychoanalysis in Zürich, Vasella practiced as an internist and specialist in psychosomatic medicine in teaching hospitals in Switzerland until 1988. He then accepted Sandoz’s offer in U.S. sales. Switching from medicine to business, he said, gave him the opportunity to do work that could benefit “not one but thousands” of people.2 He rose rapidly in Sandoz’s marketing organization in both the U.S. and Switzerland, becoming CEO of Sandoz pharmaceuticals in 1995. When Krauer retired in 1999, Vasella was also elected board chair, giving him the dual mandate.
Novartis was organized into three main businesses: health care (59% of sales), agribusiness (28%), and nutrition (13%), with the world’s largest agribusiness company, second largest pharmaceutical company (4.4% of global drug market), and Europe’s largest health food producer.3 The chemicals business was spun-off after the merger as Ciba Specialty Chemicals. In pharmaceuticals, Novartis held leading positions in several therapeutic areas, including immunology and inflammatory diseases, and strong positions in central nervous system disorders, cardiovascular, endocrine and metabolic diseases, oncology, dermatology and asthma.4
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Novartis: Leading a Global Enterprise 413-096
Sandoz’s negotiating team for the merger consisted of Vasella, head of Sandoz’s pharmaceutical business, CFO Raymond Breu, General Counsel Urs Barlocher and Alex Jetzer, CEO of Sandoz. “The merger process itself went relatively smoothly, but the cultural differences between the two companies were surprising,” Barlocher observed. “At first I thought the talk about it was a bit ridiculous, but later I realized there were huge differences.” Breu observed, “Sandoz had a command and control culture, led by CEO Marc Moret. Ciba’s culture was one of constant debate, but implementation discipline wasn’t there.”
Former McKinsey Director Henri Vanni, who joined the Novartis board in 2011, recalled, “Ciba and Sandoz were two mid-tier pharmaceutical companies that were losing ground to the American players who were moving much faster in globalizing industry. The two companies had very different management approaches: Ciba had a more Swiss culture, with centralized research and large corporate functions, with thorough but slow decision-making. Sandoz had a more international culture, with a more agile organization and greater business decentralization, including research, and with quick top down decision making.” Vanni noted, “Vasella’s leadership was central to the new firm. He has a passion for the American way of doing business—moving rapidly to get results with a top-down style, very much aspiration-driven. Ciba’s style featured more extensive discussion, evaluating all possibilities, somehow slowing down decisions. Dan’s ability to have fast but thorough analytical discussions is pretty unique. He follows the reasoning, understanding fast scientific and business issues, before deciding the right thing to do.”
Creating a New Culture
Vasella wanted to create a dynamic global company that would be highly competitive around the world, far exceeding what Sandoz and Ciba had been. To him, that meant a results-oriented company with high aspirations and very clear values. He noted, “Novartis should have a worldwide reputation for successfully launching breakthrough products; be a company feared and respected by competition, where the best people want to work and inspire each other with a sense of pride; and be our customer’s reference for quality of products and services. Novartis should be one of the fastest- growing, most profitable companies in each business we are in.”5
The early years focused on building the global organization Novartis needed to realize these goals. Recognizing cultural differences between the companies, Vasella decided Novartis needed a new culture built on the strengths of each. He knew building Novartis into a global structure required creating a meritocracy providing advancement opportunities for talented people regardless of national origin. “To create a new culture, Dan hired many talented people from outside,” said Juergen Brokatzky-Geiger, human resources head. “In the early days 80% of openings in top positions went to people from other companies. Today 80% of our executives come from within.”
To put a closed-loop performance management system in place, Vasella and his team installed new controls and reporting. Some employees interpreted that to mean Vasella did not trust them. “When you deliver results, you get rewarded with greater autonomy,” he explained. “Big words aren’t credible, only results. This was a difficult transition for some people. It took more time than I anticipated turning around the attitudes in both companies.” The company spent two years bringing together its far-flung operations, while delivering promised cost savings from the merger of $1.4 billion over three years by cutting 12,000 jobs but leaving research and development spending intact. This resulted in one-time restructuring charges of $2.5 billion offset by extraordinary after-tax gains from divestitures of $1 billion. At the time Vasella said that more acquisitions were likely but “we are going to stick with the industrial portfolio we have—and not diversify.”
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413-096 Novartis: Leading a Global Enterprise
Vasella, who was always thinking ahead, had a reputation for challenging his staff. He could also be critical and demanding. Barlocher noted that Vasella had made a few key hiring mistakes and could be unforgiving of people who crossed or disappointed him. “You can argue with Daniel, but you need a good relationship, good arguments, and past successes. Sandoz was always ruled by dictators. Moret was used to dominating, and Daniel is also very dominant.”
Helmut Sihler, former vice chairman and lead director at Novartis from 1996 to 2006, said, “As I saw Vasella with the board, I was impressed with his ability, his intelligence, and his diplomacy. You could reach him, unlike many CEOs who have a wall outside of their egos that you cannot get through. Dan had all the prerequisites to be a global leader.” Added Vanni, “Dan created a culture of open debate, where everybody participated. He isn’t afraid to put a question on the table and say, ‘I’m not prepared yet to finalize a decision, but here’s what I think. What is your opinion?’”
In 1996, Vasella engaged Harvard Business School (HBS) to help him achieve a new company culture by bringing top executives to programs created by HBS faculty. “We needed to become one company,” he explained, “that was more Anglo-Saxon because that business model is much more successful. Our benchmarks were American companies.” He continued: “One way to bridge differences is learning new things together in teams and taking people out of their normal comfort zone. We wanted to get them out of their offices and into the classroom. We had programs at HBS, Basel or Bürgenstock, Switzerland, Shanghai and Mumbai—the latter two were emerging centers many executives had never visited.”
The spirit of innovation and development of new business models were top priorities, along with financial discipline and ensuring the organization delivered what it promised. “Within a year we implemented the finance system and monthly performance against targets,” Breu explained. “Ciba didn’t even have comprehensive monthly reporting. Once your systems are in place, the organization adapts to the discipline. Within three years the performance-based culture fully took hold.”

supply chain

supply chain week 6 DQs

Week 6 Questions
10-15 years ago, sustainable business development or business sustainability were rarely used terms – you could not find them in most business texts.  By 2000, few trade publications began to call out this “new” business perspective – some thought it was just the next new business fad or trend. But, is it really so “new” – is it a fad?  Why has this concept taken off so rapidly in the past 10 years?  How has it changed Operations and Supply Change Management?    Make sure you have read the specific requirements for your original posting and your subsequent peer responses. (450 words 2 citations) due in 48 hours Wednesday 6pm NYC time
What did you learn from this Supply chain Management?  What tools and techniques will you apply in your current or next management opportunity?  Make sure you have read the specific requirements for your original posting and your subsequent peer responses.  (400 words 2 citations) Due Friday midnight NYC time

social responsibilities-Community Outreach & Respect

Chose one news article from either link below that relates to your personal interests and discuss how that article relates to our weekly material. Tell your instructor what the article was about and how the article relates to our learning content this week. Be creative with your thoughts on how you link the article to our course material). You should post the evaluation of the article at the end of your response to the discussion questions each week (Include this section as part of your 250-word response).
BUSINESS NEWS FEED #1
BUSINESS NEWS FEED #2
Additional required questions this week:
Use our Library AND our weekly reading material to answer the following:
What are a few of the types of c that businesses have? How might different types of leaders view the importance of socially responsible programs?
Discuss a few of the ethical pros of implementing social responsibility programs in organizations. Our reading content from Weiss (Chapter #5) talks about responsibility. Which of the sections (5.1, 5.2, 5.3, 5.4 or 5.5) did you find most interesting? Why? How will the content help you in your personal or professional life? Cite specific examples to support your thoughts. Thanks.
Instructions:  Your initial post should be at least 250 words.  Please respond to at least 2 other students.  Responses should be a minimum of 100 words and include direct questions. Please review the forum grading rubrics in order to understand how your responses in the forum will be graded.